Data Architecture and Tools

SPARC’s architecture ensures that data are:

• Findable through unified indexing
• Accessible via controlled permissions
• Interoperable using standard vocabularies and ontologies
• Reusable through metadata-rich documentation

Key components include:

• Secure authentication and identity management
• Role-based access
• Data minimisation and controlled sharing
• Full alignment with EU data protection requirements

The architecture supports:

• Clinical data
• Genomic sequences and variant calls
• Liquid biopsy results
• Imaging and pathology data
• Treatment and outcome information

These streams combine to produce a holistic patient profile.

SPARC deploys tools that assist in:

• Variant interpretation
• Identification of clinically actionable findings
• Literature evidence retrieval
• Treatment option mapping
• Preparing MTB case summaries

These tools improve the precision and consistency of clinical recommendations.